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Causes of Leukemia Print E-mail
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Health News - Bones (Orthopaedics)
Tuesday, 04 November 2008

eukemia causes are still unknown. In present, medical science isn’t able to create the particular leukemia causes. However, a strong connection between certain genetic factors and the development of the disease has been revealed. Leukemia occurs on the background of genetic failure that causes the excessive production of incomplete, partly matured blood cells. Also, leukemia has a hereditary character, allowing the transmission of genetic predispositions to disease from one generation to another. Although many factors are known to contribute to the development of leukemia, they alone can’t be considered leukemia causes.


The cause of acute leukemia is unknown. The only thing that one can say for certain is that some people are at a higher risk of getting the disease than others. People who are exposed to radiations or certain chemicals have the maximum chance of contracting the disease. In addition, there is the hereditary reason. It has been seen that children receive the defective gene from their mother and this gene may lead to acute leukemia. People who have leukemia tend to bruise simply or bleed simply from the nose and gums. In addition to weak immune system, there is a common feeling of weakness and unexplained weight loss. The disease by itself does not have any particular symptoms.



In normal condition, these stem cells develop either into red blood cells, white blood cells or platelets, into a controlled way. Leukemia perturbs the normal development of blood cells and causes the accumulation of partly developed cells, that aren’t able to fulfill their role inside the organism. Judging by the speed of development and the persistence of the disorder, there are 2 types of leukemia: acute leukemia and chronic leukemia. Acute leukemia differs from chronic leukemia by the levels that stem cells are able to reach in their development (stem cells that present anomalies still manage to partly develop and either resemble immature cells or full, normal white blood cells).


Leukemia is a bone marrow disorder that arises when one abnormal white blood cell begins to continuously imitate itself. Leukemia, which exactly means "white blood" in Greek, occurs when there is an excess of abnormal white blood cells in the blood. The disease regularly starts in the white blood cells. The blood-forming (hematopoietic) cells of the bone marrow make leukocytes to protect the body against infectious organisms, like viruses and bacteria. If the cells reach the central nervous system and build up in the cerebrospinal fluid that support s the brain and spinal column, they can cause headaches and seizures.


Chances of survival are better with the combination of ATRA and chemotherapy than chemotherapy alone. This is owing to ATRA combined with chemotherapy accounts for a somewhat higher rate of full remissions while allowing significantly fewer relapses. Maintenance cure with ATRA, and probably with low-dose chemotherapy, further reduces the occurrence of relapse. The advent of ATRA therapy has revolutionized the treatment of promyelocytic leukemia and obviously improved the prognosis.


A certain cause of Leukemia is not yet known as it can affect persons of all ages and both sexes. A link but between leukemia and benzene prolonged exposure or high doses of radiations could be established. But most cases cannot be rationally explained. The main goal of the Leukemia treatment is to annihilate all existing abnormal cells in blood and bone marrow. A full remission means no left trace of cancerous modifications. Some of the treated cases show a reoccurrence of the disease with other signs and symptoms.

About the Author:
Johnsmith


 
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